SEC inhibitor KL-1 ( KL-1 )

产品货号. M24926 CAS No. 900308-84-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

SEC inhibitor KL-1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

SEC 抑制剂 KL-1 对 AFF4-CCNT1 相互作用表现出剂量依赖性抑制作用 (Ki: 3.48 μM)。
产品描述

SEC inhibitor KL-1 exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 3.48 μM). SEC inhibitor KL-1 is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4.
体外实验

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体内实验

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同义词

KL-1
通路

Others
靶点

Other Targets
受体

SEC
研究领域

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适应症

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1.Liang K, et al. Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced CancerTherapy. Cell. 2018 Oct 18;175(3):766-779.

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