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SEC inhibitor KL-1

CAS No. 900308-84-1

SEC inhibitor KL-1 ( KL-1 )

产品货号. M24926 CAS No. 900308-84-1

SEC inhibitor KL-1 exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 3.48 μM).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1126 有现货
10MG ¥1798 有现货
25MG ¥3070 有现货
50MG ¥4633 有现货
100MG ¥6585 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    SEC inhibitor KL-1
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    SEC inhibitor KL-1 exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 3.48 μM).
  • 产品描述
    SEC inhibitor KL-1 exhibits a dose-dependent inhibitory effect on AFF4-CCNT1 interaction (Ki: 3.48 μM). SEC inhibitor KL-1 is a potent, selective super elongation complex (SEC) inhibitor and disrupts the interaction between the SEC scaffolding protein AFF4.
  • 同义词
    KL-1
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    SEC
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    900308-84-1
  • 分子量
    345.8
  • 分子式
    C18H16ClNO4
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:41.67 mg/mL (120.51 mM; Need ultrasonic)
  • SMILES
    CC1=C(C=C(C=C1)Cl)NC(=O)C(=O)CC(=O)C2=CC(=CC=C2)OC
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Liang K, et al. Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced CancerTherapy. Cell. 2018 Oct 18;175(3):766-779.
产品手册
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